ATIC (clone 3H12-C9-H9), anti-human, mouse, rat antibody
€295.00
In stock
SKU
AC-ABV12062-100
Catalog Number: AC-ABV12062-100
Size: 100 µg
Host: Mouse IgG
Applications: WB
Datasheet
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Size: 100 µg
Host: Mouse IgG
Applications: WB
Datasheet
Request Information
Background:
This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria.
Other Names:
Bifunctional purine biosynthesis protein PURH, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase, AICAR transformylase, IMP cyclohydrolase, IMP synthase, Inosinicase
Primary Accession: P31939
Gene Name: ATIC (HGNC:794)
Gene ID: 471
This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria.
Other Names:
Bifunctional purine biosynthesis protein PURH, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase, AICAR transformylase, IMP cyclohydrolase, IMP synthase, Inosinicase
Primary Accession: P31939
Gene Name: ATIC (HGNC:794)
Gene ID: 471
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