ATP1A1 polyclonal, anti-human, rat

Quantity: 100 µg

Background:
The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene.

Description:
Rabbit IgG polyclonal antibody for Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) detection. Tested with WB in Human, Rat.

Synonyms:
A1A1 antibody, AT1A1 antibody, AT1A1_HUMAN antibody, ATP1A1 antibody, Atpa-1 antibody, ATPase Na+/K+ transporting alpha 1 polypeptide antibody, BC010319 antibody, EC 3.6.3.9 antibody, MGC3285 antibody, MGC38419 antibody, MGC51750 antibody, Na K ATPase alpha A catalytic polypeptide antibody, Na K ATPase catalytic subunit alpha A protein antibody, Na(+)/K(+) ATPase 1 antibody, Na(+)/K(+) ATPase alpha-1 subunit antibody, Na+/K+ ATPase alpha 1 subunit antibody, Na+/K+ ATPase 1 antibody, Nkaa1b antibody, Sodium potassium ATPase alpha 1 polypeptide antibody, Sodium pump 1 antibody, Sodium pump subunit alpha-1 antibody, sodium-potassium ATPase catalytic subunit alpha-1 antibody, Sodium/potassium transporting ATPase alpha 1 chain antibody, Sodium/potassium-transporting ATPase subunit alpha-1 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human ATP1A1 (7-34aa RDKYEPAAVSEQGDKKGKKGKKDRDMDE), different from the related mouse sequence by three amino acids, and from the related rat sequence by four amino acids.A synthetic peptide corresponding to a sequence at the N-terminus of human ATP1A1 (7-34aa RDKYEPAAVSEQGDKKGKKGKKDRDMDE), different from the related mouse sequence by three amino acids, and from the related rat sequence by four amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.