ATP1A1 Polyclonal Antibody

Background:
The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Area: Cancer, Metabolism, Neuroscience, Signal Transduction, Tags and Cell Markers

Synonyms:
ATP1A1, ATPase Na+/K+ transporting subunit alpha 1, ATP1A, CMT2DD, HOMGSMR2

Immunogen: A synthetic peptide of human ATP1A1 (NP_000692.2).

Swissprot: P05023
Gene ID: 476

Calculated MW: 74 kDa/109 kDa/112 kDa/113 kDa
Observed MW: 115 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.