ATP2A1 polyclonal, anti-human, mouse

Background:
This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms.

Synonyms: ATP2A, SERCA1

Cellular Location: Cytoplasm

Immunogen:
A synthetic peptide of human ATP2A1

Gene Symbol: ATP2A1

Gene ID: 487

Swiss prot: O14983

Calculated MW: 110kDa

Recommended dilution:
WB 1:200-1000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.