ATP2A2 Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP17013c
Background:
This gene encodes one of the SERCA Ca(2+)-ATPases, whichare intracellular pumps located in the sarcoplasmic or endoplasmicreticula of muscle cells. This enzyme catalyzes the hydrolysis ofATP coupled with the translocation of calcium from the cytosol intothe sarcoplasmic reticulum lumen, and is involved in regulation ofthe contraction/relaxation cycle. Mutations in this gene causeDarier-White disease, also known as keratosis follicularis, anautosomal dominant skin disorder characterized by loss of adhesionbetween epidermal cells and abnormal keratinization. Alternativesplicing results in multiple transcript variants encoding differentisoforms.
Other Names:
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2, SERCA2, SR Ca(2+)-ATPase 2, Calcium pump 2, Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform, Endoplasmic reticulum class 1/2 Ca(2+) ATPase, ATP2A2, ATP2B
Gene Name: ATP2A2 (HGNC:812)
Gene ID: 488
Primary Accession: P16615
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes one of the SERCA Ca(2+)-ATPases, whichare intracellular pumps located in the sarcoplasmic or endoplasmicreticula of muscle cells. This enzyme catalyzes the hydrolysis ofATP coupled with the translocation of calcium from the cytosol intothe sarcoplasmic reticulum lumen, and is involved in regulation ofthe contraction/relaxation cycle. Mutations in this gene causeDarier-White disease, also known as keratosis follicularis, anautosomal dominant skin disorder characterized by loss of adhesionbetween epidermal cells and abnormal keratinization. Alternativesplicing results in multiple transcript variants encoding differentisoforms.
Other Names:
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2, SERCA2, SR Ca(2+)-ATPase 2, Calcium pump 2, Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform, Endoplasmic reticulum class 1/2 Ca(2+) ATPase, ATP2A2, ATP2B
Gene Name: ATP2A2 (HGNC:812)
Gene ID: 488
Primary Accession: P16615
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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