ATP2B4 polyclonal (C-term), anti-human

Background:
The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 4. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq].

Other Names:
Plasma membrane calcium-transporting ATPase 4, PMCA4, Matrix-remodeling-associated protein 1, Plasma membrane calcium ATPase isoform 4, Plasma membrane calcium pump isoform 4, ATP2B4, ATP2B2, MXRA1

Target/Specificity:
This ATP2B4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1174-1202 amino acids from the C-terminal region of human ATP2B4.

Antigen Region:
1174-1202

Antigen Type: Synthetic Peptide

Gene Name: ATP2B4 (HGNC:817)
Gene ID: 493
Primary Accession: P23634
NCBI Accession: NP_001001396.1;NP_001675.3
Other Accession: NP_001675.3;NP_001001396.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.