ATP6V0A4 Blocking Peptide (Center)
€363.00
In stock
SKU
AC-BP5369c
Background:
This gene encodes a component of vacuolar ATPase(V-ATPase), a multisubunit enzyme that mediates acidification ofintracellular compartments of eukaryotic cells. V-ATPase dependentacidification is necessary for such intracellular processes asprotein sorting, zymogen activation, receptor-mediated endocytosis,and synaptic vesicle proton gradient generation. V-ATPase iscomposed of a cytosolic V1 domain and a transmembrane V0 domain.The V1 domain consists of three A and three B subunits, two Gsubunits plus the C, D, E, F, and H subunits. The V1 domaincontains the ATP catalytic site. The V0 domain consists of fivedifferent subunits: a, c, c', c'', and d. This gene is one of fourgenes in man and mouse that encode different isoforms of the asubunit. Alternatively spliced transcript variants encoding thesame protein have been described. Mutations in this gene areassociated with renal tubular acidosis associated with preservedhearing.
Other Names:
V-type proton ATPase 116 kDa subunit a isoform 4, V-ATPase 116 kDa isoform a4, Vacuolar proton translocating ATPase 116 kDa subunit a isoform 4, Vacuolar proton translocating ATPase 116 kDa subunit a kidney isoform, ATP6V0A4, ATP6N1B, ATP6N2
Target/Specificity:
The synthetic peptide sequence is selected from aa 250-261 of HUMAN ATP6V0A4
Gene Name: ATP6V0A4
Gene ID: 50617
Primary Accession: Q9HBG4
Other Accession: NP_570856.2;NP_570855.2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a component of vacuolar ATPase(V-ATPase), a multisubunit enzyme that mediates acidification ofintracellular compartments of eukaryotic cells. V-ATPase dependentacidification is necessary for such intracellular processes asprotein sorting, zymogen activation, receptor-mediated endocytosis,and synaptic vesicle proton gradient generation. V-ATPase iscomposed of a cytosolic V1 domain and a transmembrane V0 domain.The V1 domain consists of three A and three B subunits, two Gsubunits plus the C, D, E, F, and H subunits. The V1 domaincontains the ATP catalytic site. The V0 domain consists of fivedifferent subunits: a, c, c', c'', and d. This gene is one of fourgenes in man and mouse that encode different isoforms of the asubunit. Alternatively spliced transcript variants encoding thesame protein have been described. Mutations in this gene areassociated with renal tubular acidosis associated with preservedhearing.
Other Names:
V-type proton ATPase 116 kDa subunit a isoform 4, V-ATPase 116 kDa isoform a4, Vacuolar proton translocating ATPase 116 kDa subunit a isoform 4, Vacuolar proton translocating ATPase 116 kDa subunit a kidney isoform, ATP6V0A4, ATP6N1B, ATP6N2
Target/Specificity:
The synthetic peptide sequence is selected from aa 250-261 of HUMAN ATP6V0A4
Gene Name: ATP6V0A4
Gene ID: 50617
Primary Accession: Q9HBG4
Other Accession: NP_570856.2;NP_570855.2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
| Is Featured? | No |
|---|
Write Your Own Review