ATP6V1B2 antibody (clone M1), anti-human
€435.00
In stock
SKU
AC-AT1241a
Catalog Number: AC-AT1241a
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: E
Request Information AC-AT1241a">Request Information
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: E
Request Information AC-AT1241a">Request Information
Background:
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.
Other Names:
V-type proton ATPase subunit B, brain isoform, V-ATPase subunit B 2, Endomembrane proton pump 58 kDa subunit, HO57, Vacuolar proton pump subunit B 2, ATP6V1B2, ATP6B2, VPP3
Antigen Type:
Recombinant Protein
Gene Name: ATP6V1B2
Gene ID: 526
NCBI Accession: NP_001684.2
Primary Accession: P21281
Other Accession: BC003100
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.
Other Names:
V-type proton ATPase subunit B, brain isoform, V-ATPase subunit B 2, Endomembrane proton pump 58 kDa subunit, HO57, Vacuolar proton pump subunit B 2, ATP6V1B2, ATP6B2, VPP3
Antigen Type:
Recombinant Protein
Gene Name: ATP6V1B2
Gene ID: 526
NCBI Accession: NP_001684.2
Primary Accession: P21281
Other Accession: BC003100
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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