ATP6V1E1 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain E subunit isoforms. Pseudogenes for this gene have been found in the genome.

Synonyms: ATP6E, ATP6E2, ATP6V1E, P31, Vma4

Cellular Location: Cytosol secreted Lysosome Endosome Plasma Membrane

Immunogen:
Recombinant protein of human ATP6V1E1

Gene Symbol: ATP6V1E1

Gene ID: 529

Swiss prot: P36543

Calculated MW: 26kDa

Recommended dilution:
WB 1:1000-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.