ATP6V1G2 antibody (clone 200000000000), anti-human, mouse, rat
€435.00
In stock
SKU
AC-AT1243a
Catalog Number: AC-AT1243a
Size: 100 µg
Isotype: mouse IgG2b Lambda
Applications: WB
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Size: 100 µg
Isotype: mouse IgG2b Lambda
Applications: WB
Request Information AC-AT1243a">Request Information
Background:
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of three V1 domain G subunit proteins. This gene had previous gene symbols of ATP6G and ATP6G2. Alternatively spliced transcript variants encoding different isoforms have been described.
Other Names:
V-type proton ATPase subunit G 2, V-ATPase subunit G 2, V-ATPase 13 kDa subunit 2, Vacuolar proton pump subunit G 2, ATP6V1G2, ATP6G, ATP6G2, NG38
Antigen Type:
Recombinant Protein
Gene Name: ATP6V1G2
Gene ID: 534
NCBI Accession: NP_001191007.1;NP_569730.1;NP_612139.1
Primary Accession: O95670
Other Accession: NM_130463
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of three V1 domain G subunit proteins. This gene had previous gene symbols of ATP6G and ATP6G2. Alternatively spliced transcript variants encoding different isoforms have been described.
Other Names:
V-type proton ATPase subunit G 2, V-ATPase subunit G 2, V-ATPase 13 kDa subunit 2, Vacuolar proton pump subunit G 2, ATP6V1G2, ATP6G, ATP6G2, NG38
Antigen Type:
Recombinant Protein
Gene Name: ATP6V1G2
Gene ID: 534
NCBI Accession: NP_001191007.1;NP_569730.1;NP_612139.1
Primary Accession: O95670
Other Accession: NM_130463
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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