ATP6V1H polyclonal (C-term), anti-human, mouse

ATP6V1H polyclonal (C-term), anti-human, mouse

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In stock
SKU
AC-AP5182B
Catalog Number: AC-AP5182B
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB25984
Applications: WB
Datasheet

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Background:
ATP6V1H encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes the regulatory H subunit of the V1 domain which is required for catalysis of ATP but not the assembly of V-ATPase.

Other Names:
V-type proton ATPase subunit H, V-ATPase subunit H, Nef-binding protein 1, NBP1, Protein VMA13 homolog, V-ATPase 50/57 kDa subunits, Vacuolar proton pump subunit H, Vacuolar proton pump subunit SFD, ATP6V1H

Target/Specificity:
This ATP6V1H antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-426 amino acids from the C-terminal region of human ATP6V1H.

Antigen Region:
400-426

Antigen Type: Synthetic Peptide

Gene Name: ATP6V1H
Gene ID: 51606
Primary Accession: Q9UI12
NCBI Accession: NP_057025.2;NP_998784.1;NP_998785.1
Other Accession: Q9TVC1; Q8BVE3; O46563
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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