ATP7A polyclonal, anti-human

Background:
This gene encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital horn syndrome. Alternatively-spliced transcript variants have been observed.

Synonyms: DSMAX；MK；MNK；SMAX3；copper-transporting ATPase 1

Cellular Location: Cytoplasm  Cell membrane

Immunogen:
A synthetic peptide of human ATP7A

Gene Symbol: ATP7A

Gene ID: 538

Swiss prot: Q04656

Calculated MW: 163/172/54/154/12kDa

Recommended dilution:
IHC 1:25-100

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.