ATP7A Polyclonal Antibody

Background:
ATPase copper transporting alpha(ATP7A) Homo sapiens This gene encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital horn syndrome. Alternatively-spliced transcript variants have been observed. [provided by RefSeq, Aug 2013],

Alternative Names:
ATP7A, MC1, MNK, Copper-transporting ATPase 1, Copper pump 1, Menkes disease-associated protein

Immunogen: The antiserum was produced against synthesized peptide derived from human ATP7A. AA range:591-640

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

GeneID: ATP7A

Storage: -20°C/1 year

NOTE: For Research Use Only