ATP7B antibody (clone 30000000000), anti-human
€435.00
In stock
SKU
AC-AT1244a
Catalog Number: AC-AT1244a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, E
Request Information AC-AT1244a">Request Information
Background:
This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).
Other Names:
Copper-transporting ATPase 2, Copper pump 2, Wilson disease-associated protein, WND/140 kDa, ATP7B, PWD, WC1, WND
Antigen Type:
Recombinant Protein
Gene Name: ATP7B
Gene ID: 540
NCBI Accession: NP_000044.2;NP_001230111.1
Primary Accession: P35670
Other Accession: NM_000053
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).
Other Names:
Copper-transporting ATPase 2, Copper pump 2, Wilson disease-associated protein, WND/140 kDa, ATP7B, PWD, WC1, WND
Antigen Type:
Recombinant Protein
Gene Name: ATP7B
Gene ID: 540
NCBI Accession: NP_000044.2;NP_001230111.1
Primary Accession: P35670
Other Accession: NM_000053
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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