ATP7B polyclonal, anti-human, mouse

Background:
This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).

Synonyms: PWD, WC1, WD, WND

Cellular Location: Cytoplasm Golgi apparatus Golgi apparatus membrane Mitochondrion Multi-pass membrane protein Multi-pass membrane protein trans-Golgi network membrane

Immunogen:
Recombinant protein of human ATP7B

Gene Symbol: ATP7B

Gene ID: 540

Swiss prot: P35670

Calculated MW: 157kDa

Recommended dilution:
WB 1:500-2000, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.