ATPIF1 Polyclonal Antibody

Background:
ATPase inhibitor, mitochondrialis anenzymethat in humans is encoded by theATPIF1gene. This gene encodes a mitochondrial ATPase inhibitor. Alternative splicing occurs at this locus and three transcript variants encoding distinct isoforms have been identified. It prevents ATPase from switching to ATP hydrolysis during collapse of the electrochemical gradient, for example during oxygen deprivation ATP synthase inhibitor forms a one to one complex with the F1 ATPase, possibly by binding at the alpha-beta interface. It is thought to inhibit ATP synthesis by preventing the release of ATP. The inhibitor has two oligomeric states, dimer (the active state) and tetramer.

Research Area: Cancer, Metabolism, Signal Transduction, Tags and Cell Markers

Synonyms:
ATIF1, ATP synthase inhibitor protein, ATPase inhibitor, ATPase inhibitor mitochondrial, ATPase inhibitor protein, ATPase inhibitory factor 1, ATPI, ATPIF 1, Atpif1, ATPIP, IF(1), IF1, Inhibitor of F(1)F(o)-ATPase, IP, MGC1167, MGC8898, mitochondrial

Immunogen: Recombinant protein of human ATPIF1

Swissprot: Q9UII2
Gene Accession: BC009677

Calculated MW: 12 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.2 mg/mL
Dilution: WB 1:1000-1:5000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-162556/sc-162558/sc-162557/sc-134962