ATRIP polyclonal antibody, anti-human, mouse, rat

Background:
ATRIP encodes an essential component of the DNA damage checkpoint. The encoded protein (ATR interacting protein) binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for ATRIP.

Research Area: Epigenetics and Nuclear Signaling

Synonyms: ATRIP, AGS1, ATR-interacting protein, ATM and Rad3-related-interacting protein

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year