ATS13 polyclonal antibody, anti-human, mouse, rat

Background:
This gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. The enzyme encoded by this gene specifically cleaves von Willebrand Factor (vWF). Defects in this gene are associated with thrombotic thrombocytopenic purpura. Alternative splicing results in multiple transcript variants.

Research Area: Signal transduction, Cancer, Cell biology

Synonyms: A disintegrin and metalloproteinase with thrombospondin motifs 13 , ADAM-TS 13, ADAM-TS13, ADAMTS-13, EC 3.4.24.87, von Willebrand factor-cleaving protease, vWF-CP, vWF-cleaving protease

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year