ATXN3 polyclonal, anti-human

Background:
Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. 

Synonyms: AT3, JOS, MJD, ATX3, MJD1, SCA3

Cellular Location: Cytoplasm Nucleus

Immunogen:
Recombinant protein of human ATXN3

Gene Symbol: ATXN3

Gene ID: 4287

Swiss prot: P54252

Calculated MW: 42kDa

Recommended dilution:
IHC 1:50-300

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.