ATXN3 polyclonal (Center), anti-human

ATXN3 polyclonal (Center), anti-human

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In stock
SKU
AC-AP9244c
Catalog Number: AC-AP9244c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB23951
Applications: WB, FC, IHC-P
Datasheet

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Background:
ATXN3 was known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers.

Other Names:
Ataxin-3, Machado-Joseph disease protein 1, Spinocerebellar ataxia type 3 protein, ATXN3, ATX3, MJD, MJD1, SCA3

Target/Specificity:
This ATXN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 261-288 amino acids from the Central region of human ATXN3.

Antigen Region:
261-288

Antigen Type: Synthetic Peptide

Gene Name: ATXN3 {ECO:0000303|PubMed:33157014, ECO:0000312|HGNC:HGNC:7106}
Gene ID: 4287
Primary Accession: P54252
NCBI Accession: NP_001121168.1;NP_001158252.1;NP_004984.2;NP_109376.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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