AUP1 polyclonal (C-term), anti-human
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In stock
SKU
AC-AP16554b
Catalog Number: AC-AP16554b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36130
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36130
Applications: WB
Datasheet
Request Information
Background:
This gene encodes a protein that contains a domain with homology to the ancient conserved region of the archain 1 gene and a domain that may be involved in binding ubiquitin-conjugating enzymes. The protein encoded by this gene has been shown to bind to the conserved membrane-proximal sequence of the cytoplasmic tail of integrin alpha(IIb) subunits. These subunits play a crucial role in the integrin alpha(IIb)beta(3) inside-out signalling in platelets and megakaryocytes that leads to platelet aggregation and thrombus formation. This gene overlaps the gene for mitochondrial serine protease 25.
Other Names:
Ancient ubiquitous protein 1, AUP1
Target/Specificity:
This AUP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 440-468 amino acids from the C-terminal region of human AUP1.
Antigen Region:
440-468
Antigen Type: Synthetic Peptide
Gene Name: AUP1 (HGNC:891)
Gene ID: 550
Primary Accession: Q9Y679
NCBI Accession: NP_853553.1
Other Accession: NP_853553.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes a protein that contains a domain with homology to the ancient conserved region of the archain 1 gene and a domain that may be involved in binding ubiquitin-conjugating enzymes. The protein encoded by this gene has been shown to bind to the conserved membrane-proximal sequence of the cytoplasmic tail of integrin alpha(IIb) subunits. These subunits play a crucial role in the integrin alpha(IIb)beta(3) inside-out signalling in platelets and megakaryocytes that leads to platelet aggregation and thrombus formation. This gene overlaps the gene for mitochondrial serine protease 25.
Other Names:
Ancient ubiquitous protein 1, AUP1
Target/Specificity:
This AUP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 440-468 amino acids from the C-terminal region of human AUP1.
Antigen Region:
440-468
Antigen Type: Synthetic Peptide
Gene Name: AUP1 (HGNC:891)
Gene ID: 550
Primary Accession: Q9Y679
NCBI Accession: NP_853553.1
Other Accession: NP_853553.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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