AURKA polyclonal, anti-human, mouse

Background:
The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.

Synonyms: AIK, ARK1, AURA, BTAK, PPP1R47, STK15, STK6, STK7

Cellular Location: Cytoplasm centriole centrosome cilium basal body cytoskeleton microtubule organizing center spindle pole

Immunogen:
A synthetic peptide of human AURKA

Gene Symbol: AURKA

Gene ID: 6790

Swiss prot: O14965

Calculated MW: 46kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.