AURKC polyclonal, anti-human, mouse, rat

Background:
This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.

Synonyms: AIE2, AIK3, ARK3, AurC, HEL-S-90, SPGF5, STK13, aurora-C

Cellular Location: Chromosome Cytoplasm Nucleus centromere cytoskeleton spindle

Immunogen:
A synthetic peptide of human AURKC

Gene Symbol: AURKC

Gene ID: 6795

Swiss prot: Q9UQB9

Calculated MW: 36kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.