AURKC Polyclonal Antibody

Background:
This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.

Research Area: Cell Biology

Synonyms:
AURKC, AIE2, AIK3, ARK3, AurC, HEL-S-90, SPGF5, STK13, aurora-C

Immunogen: A synthetic peptide of human AURKC

Swissprot: Q9UQB9
Gene ID: 6795

Calculated MW: 32 kDa/33 kDa/35 kDa
Observed MW: 36 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.