Aurora B polyclonal, anti-human

Background:
Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation.

Synonyms: AURKB, AIK2, AIM1, AIRK2

Cellular Location: Nucleus Cytoplasm

Immunogen:
A synthetic peptide of human Aurora B

Gene Symbol: Aurora B

Gene ID: 9212

Swiss prot: Q96GD4

Calculated MW: 39/35/16kDa

Recommended dilution:
WB 1:10000-15000, IHC 1:50-200

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.