AVPR1B rabbit polyclonal, anti-human, mouse, rat

Backgroud: The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known.

Synonyms: AVPR1B, AVPR3, VPR3, Vasopressin V1b receptor, V1bR, AVPR V1b, AVPR V3, Antidiuretic hormone receptor 1b, Vasopressin V3 receptor

Gene Name: AVPR1B

Gene ID: 553

SwissProt ID: P47901

Purification: Affinity Purified

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.