Axin 2 rabbit polyclonal, anti-human, mouse, rat

Backgroud: Axin1 (Axis inhibition protein 1) and Axin2 are multidomain scaffold proteins that negatively regulate Wnt signaling. Axin1 interacts with APC, GSK-3β, Dvl, and β-catenin and promotes the GSK-3β-mediated phosphorylation and subsequent degradation of β-catenin .Down-regulates beta-catenin.

Synonyms: Axil, Axin like protein, Axin2, Axis inhibition protein 2, Conductin

Gene Name: AXIN2

Gene ID: 8313

SwissProt ID: Q9Y2T1

Purification: Affinity Chromatography

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.