AZU1 polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP14972C
Catalog Number: AC-AP14972C
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34944
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34944
Applications: WB
Datasheet
Request Information
Background:
Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. The protein encoded by this gene is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation.
Other Names:
Azurocidin, Cationic antimicrobial protein CAP37, Heparin-binding protein, HBP, AZU1
Target/Specificity:
This AZU1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-96 amino acids from the Central region of human AZU1.
Antigen Region:
67-96
Antigen Type: Synthetic Peptide
Gene Name: AZU1 (HGNC:913)
Gene ID: 566
Primary Accession: P20160
NCBI Accession: NP_001691.1
Other Accession: NP_001691.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. The protein encoded by this gene is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation.
Other Names:
Azurocidin, Cationic antimicrobial protein CAP37, Heparin-binding protein, HBP, AZU1
Target/Specificity:
This AZU1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-96 amino acids from the Central region of human AZU1.
Antigen Region:
67-96
Antigen Type: Synthetic Peptide
Gene Name: AZU1 (HGNC:913)
Gene ID: 566
Primary Accession: P20160
NCBI Accession: NP_001691.1
Other Accession: NP_001691.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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