B Raf polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
BRAF (v-raf murine sarcoma viral oncogene homolog B1) is a human gene that makes a protein called B-Raf. It is a member of the Raf kinase family of growth signal transduction protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. It is mapped to 7q34. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. The BRAF protein is also involved in sending signals inside cells, which are involved in directing cell growth.

Description:
Rabbit IgG polyclonal antibody for Serine/threonine-protein kinase B-raf (BRAF) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
FLJ95109 antibody, 94 kDa B raf protein antibody, B raf 1 antibody, B raf 1 antibody, B Raf proto oncogene serine threonine protein kinase antibody, B Raf proto oncogene serine threonine protein kinase antibody, B-Raf proto-oncogene serine/threonine-protein kinase (p94) antibody, BRAF 1 antibody, BRaf antibody, BRaf antibody, BRAF_HUMAN antibody, BRAF1 antibody, BRAF1 antibody, cRmil antibody, MGC126806 antibody, MGC138284 antibody, Murine sarcoma viral (v-raf) oncogene homolog B1 antibody, Murine sarcoma viral (v-raf) oncogene homolog B1 antibody, Murine sarcoma viral v raf oncogene homolog B1 antibody, Murine sarcoma viral v raf oncogene homolog B1 antibody, NS7 antibody, oncogene BRAF1 antibody, p94 antibody, p94 antibody, Proto-oncogene B-Raf antibody, Proto-oncogene c-Rmil antibody, RAFB 1 antibody, RAFB1 antibody, RAFB1 antibody, RMIL antibody, Serine/threonine-protein kinase B-raf antibody, v raf murine sarcoma viral oncogene homolog B antibody, v raf murine sarcoma viral oncogene homolog B1 antibody, v raf murine sarcoma viral oncogene homolog B1 antibody, v-Raf murine sarcoma viral oncogene homolog B1 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human B Raf recombinant protein (Position: A38-V230). Human B Raf shares 81% amino acid (aa) sequence identity with mouse B Raf.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.