B-RAF polyclonal (S601), anti-human

B-RAF polyclonal (S601), anti-human

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In stock
SKU
AC-AP7810j
Catalog Number: AC-AP7810j
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB10945
Applications: IHC-P, WB
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Background:
BRAF, a member of the RAF subfamily of Ser/Thr protein kinases, is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neurons. This cytoplasmic protein is expressed in brain and testis. Defects in BRAF are involved in a wide range of cancers including lung cancer and non-Hodgkin lymphoma (NHL). This protein contains 1 zinc-dependent phorbol-ester and DAG binding domain.

Other Names:
Serine/threonine-protein kinase B-raf, Proto-oncogene B-Raf, p94, v-Raf murine sarcoma viral oncogene homolog B1, BRAF, BRAF1, RAFB1

Target/Specificity:
This B-RAF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 580-609 amino acids from human B-RAF.

Antigen Region:
580-609

Antigen Type: Synthetic Peptide

Gene Name: BRAF (HGNC:1097)
Gene ID: 673
Primary Accession: P15056
NCBI Accession: NP_004324.2
Other Accession: P28028; Q04982
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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