B2M Polyclonal Antibody

Background:
Beta-2-microglobulin (B2M) is a component of MHC class I molecules,which are present on the surface of nearly all nucleated cells. It can be found in body fluids under physiologic conditions as a result of shedding from cell surfaces or intracellular release. B2M has various biological functions,including antigen presentation. Investigations reveal that increased synthesis and release of B2M are present in several malignant diseases.

Research Area: Cancer, Cardiovascular

Synonyms:
B2M, B2MG, Beta 2 microglobin, Beta 2 microglobulin, Beta 2 microglobulin precursor, Beta chain of mhc class 1 proteins, Beta chain of MHC class I molecules, Beta-2-microglobulin form pI 5.3, CDABP0092, Hdcma22p, IMD43

Immunogen: Recombinant Human Beta-2-microglobulin protein

Swissprot: P61769
Gene ID: 567

Calculated MW: 13 kDa
Observed MW: 13 kDa

Purification Method: Antigen Affinity Purification

Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: WB 1:1000-1:3000 IHC 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.