B4GALT4 antibody (clone 500), anti-human

B4GALT4 antibody (clone 500), anti-human

€435.00
In stock
SKU
AC-AT1256a
Catalog Number: AC-AT1256a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, E
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Background:
This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene appears to mainly play a role in glycolipid biosynthesis. Two alternatively spliced transcript variants have been found for this gene.

Other Names:
Beta-1,4-galactosyltransferase 4, Beta-1,4-GalTase 4, Beta4Gal-T4, b4Gal-T4, 241-, UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 4, UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 4, N-acetyllactosamine synthase, Nal synthase, Lactotriaosylceramide beta-1,4-galactosyltransferase, Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase, B4GALT4

Antigen Type:
Recombinant Protein

Gene Name: B4GALT4 {ECO:0000303|PubMed:17690104, ECO:0000312|HGNC:HGNC:927}
Gene ID: 8702
NCBI Accession: NP_003769.1;NP_997708.1
Primary Accession: O60513
Other Accession: NM_003778
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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