BACE1 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients.

Synonyms: ASP2, BACE, HSPC104

Cellular Location: Cell surface Cytoplasmic vesicle membrane Endoplasmic reticulum Endosome Golgi apparatus Membrane Single-pass type I membrane protein trans-Golgi network

Immunogen:
Recombinant protein of human BACE1

Gene Symbol: BACE1

Gene ID: 23621

Swiss prot: P56817

Calculated MW: 56kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.