BACE1 polyclonal (N-term), anti-human, mouse
€0.00
In stock
SKU
AC-AP7774b
Catalog Number: AC-AP7774b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB16874
Applications: IHC-P, WB
Datasheet
Request Information
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB16874
Applications: IHC-P, WB
Datasheet
Request Information
Background:
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is BACE. This protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.
Other Names:
Beta-secretase 1, Aspartyl protease 2, ASP2, Asp 2, Beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme 1, Memapsin-2, Membrane-associated aspartic protease 2, BACE1, BACE, KIAA1149
Target/Specificity:
This BACE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-70 amino acids from the N-terminal region of human BACE1.
Antigen Region:
38-70
Antigen Type: Synthetic Peptide
Gene Name: BACE1 (HGNC:933)
Gene ID: 23621
Primary Accession: P56817
NCBI Accession: NP_001193978.1;NP_036236.1;NP_620427.1;NP_620428.1;NP_620429.1
Other Accession: P56819; P56818; Q2HJ40
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is BACE. This protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.
Other Names:
Beta-secretase 1, Aspartyl protease 2, ASP2, Asp 2, Beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme 1, Memapsin-2, Membrane-associated aspartic protease 2, BACE1, BACE, KIAA1149
Target/Specificity:
This BACE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-70 amino acids from the N-terminal region of human BACE1.
Antigen Region:
38-70
Antigen Type: Synthetic Peptide
Gene Name: BACE1 (HGNC:933)
Gene ID: 23621
Primary Accession: P56817
NCBI Accession: NP_001193978.1;NP_036236.1;NP_620427.1;NP_620428.1;NP_620429.1
Other Accession: P56819; P56818; Q2HJ40
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
|---|
Write Your Own Review