BACE1C polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP6103a
Catalog Number: AC-AP6103a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB2119-2120
Applications: IHC-P, FC, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB2119-2120
Applications: IHC-P, FC, WB
Datasheet
Request Information
Background:
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the BACE1. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.
Other Names:
Beta-secretase 1, Aspartyl protease 2, ASP2, Asp 2, Beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme 1, Memapsin-2, Membrane-associated aspartic protease 2, BACE1, BACE, KIAA1149
Target/Specificity:
This BACE1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125-154 amino acids from the Central region of human BACE1C.
Antigen Region:
125-154
Antigen Type: Synthetic Peptide
Gene Name: BACE1 (HGNC:933)
Gene ID: 23621
Primary Accession: P56817
NCBI Accession: NP_001193978.1;NP_036236.1;NP_620427.1;NP_620428.1;NP_620429.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the BACE1. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.
Other Names:
Beta-secretase 1, Aspartyl protease 2, ASP2, Asp 2, Beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme 1, Memapsin-2, Membrane-associated aspartic protease 2, BACE1, BACE, KIAA1149
Target/Specificity:
This BACE1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125-154 amino acids from the Central region of human BACE1C.
Antigen Region:
125-154
Antigen Type: Synthetic Peptide
Gene Name: BACE1 (HGNC:933)
Gene ID: 23621
Primary Accession: P56817
NCBI Accession: NP_001193978.1;NP_036236.1;NP_620427.1;NP_620428.1;NP_620429.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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