BACE2 Polyclonal Antibody

Background:
This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Cell Biology, Neuroscience

Synonyms:
ALP 56, ALP56, Asp 1, ASP1, ASP21, Aspartic Like Protease 56kDa, Aspartic-like protease 56 kDa, Aspartyl protease 1, BACE 2, Bace2, BACE2, Beta Secretase 2, Beta Site Amyloid Beta A4 Precursor Protein Cleaving Enzyme 2, Beta-secretase 2, Beta-site amyloid precursor protein cleaving enzyme 2, Beta-site APP cleaving enzyme 2, Down region aspartic protease, Downs Syndrome Region Aspartic Protease, DRAP, Memapsin 1, Memapsin-1, Membrane associated aspartic protease 1, Membrane-associated aspartic protease 1, Theta-secretase

Immunogen: Synthetic peptide of human BACE2

Swissprot: Q9Y5Z0
Gene Accession: NP036237

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.8 mg/mL
Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.