BAD (clone 1G5B3), anti-human

BAD (clone 1G5B3), anti-human

€0.00
In stock
SKU
BT-MCA3850
Catalog Number: BT-MCA3850
Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity: human
Application(s): WB, FCM
Datasheet
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Background:
The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.

Research Area: Cell Biology

Synonyms: BBC2, BCL2L8

Immunogen: Purified recombinant fragment of human BAD (AA: FULL(1-168)) expressed in E. Coli.

Formulation: Purified antibody in PBS with 0.05% sodium azide.

Storage:
4°C|-20°C for long term storage
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