Bad polyclonal, anti-human, mouse, rat, primate antibody
€295.00
In stock
SKU
AC-ABV10022-100
Catalog Number: AC-ABV10022-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB, IHC, IP
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB, IHC, IP
Datasheet
Request Information
Background:
The Bcl-2 (B-cell leukemia/lymphoma 2) family proteins function to either inhibit (Bcl-2 and Bcl-XL) or promote (Bax and Bad) apoptosis. Similar to other family member, Bad also exhibits sequence homology to Bcl-2. Bad can selectively dimerize with Bcl-xL and Bcl-2, but not with Bax, Bcl-xs, Mcl-1, or itself. In mammalian cells, Bad binds more strongly to Bcl-xL than Bcl-2. This may explain why Bad reverse the death repressor activity of Bcl-xL, but not that of Bcl-2
Other Names:
BBC6, BCL2L8, Bcl-2-binding component 6, Bcl-2-like 8 protein
Primary Accession: Q61337.1
Concentration (mg/ml): 0.5 mg/ml
The Bcl-2 (B-cell leukemia/lymphoma 2) family proteins function to either inhibit (Bcl-2 and Bcl-XL) or promote (Bax and Bad) apoptosis. Similar to other family member, Bad also exhibits sequence homology to Bcl-2. Bad can selectively dimerize with Bcl-xL and Bcl-2, but not with Bax, Bcl-xs, Mcl-1, or itself. In mammalian cells, Bad binds more strongly to Bcl-xL than Bcl-2. This may explain why Bad reverse the death repressor activity of Bcl-xL, but not that of Bcl-2
Other Names:
BBC6, BCL2L8, Bcl-2-binding component 6, Bcl-2-like 8 protein
Primary Accession: Q61337.1
Concentration (mg/ml): 0.5 mg/ml
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