Bag1 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
BAG family molecular chaperone regulator 1(BAG1) is a protein that in humans is encoded by the BAG1 gene. Human BAG1 is mapped to chromosome 9p12, a region associated with hereditary disorders that may involve developmental dysregulation of programmed cell death. The Bag1 protein is rich in glutamic acid residues. Its deduced 274-amino acid protein has a calculated molecular mass of 31 KD. Being the BCL-2-associated athanogene, Bag1 enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms.

Description:
Rabbit IgG polyclonal antibody for BAG family molecular chaperone regulator 1 (BAG1) detection. Tested with WB, IHC-P, ICC in Human, Rat.

Synonyms:
Bcl-2-associated athanogene 1

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human Bag1(322-344aa DTVEQNICQETERLQSTNFALAE), different from the related mouse sequence by two amino acids.A synthetic peptide corresponding to a sequence at the C-terminus of human Bag1(322-344aa DTVEQNICQETERLQSTNFALAE), different from the related mouse sequence by two amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB, IHC-P, ICC

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.