BAG1 Polyclonal Antibody

Background:
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.

Research Area: Cancer, Cell Biology, Cardiovascular, Metabolism

Synonyms:
Bag 1, BAG family molecular chaperone regulator 1, BAG-1, BAG1, BAG1, BCL 2 Associated Athanogene 1, BCL 2 associated athanogene, BCL 2 binding athanogene 1, Bcl-2-associated athanogene 1, BCL2 associated athanogene 1, BCL2 associated athanogene, Glucocorticoid receptor-associated protein RAP46, HAP1, Haptoglobin, RAP 46, RAP46

Immunogen: Recombinant protein of human BAG1

Swissprot: Q99933
Gene Accession: BC001936

Calculated MW: 39 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.2 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-31680/sc-31681/sc-31682/sc-939/sc-8348