BAG1 Polyclonal Antibody

Background:
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.

Research Area: Cancer, Cell Biology, Cardiovascular, Metabolism

Synonyms:
BAG1, BAG-1, HAP, RAP46

Immunogen: Recombinant fusion protein of human BAG1 (NP_001165886.1).

Swissprot: Q99933
Gene ID: 573

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "IHC 1:50-1:200 IF 1:20-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.