BAG2 antibody (clone 6.0E+12), anti-human
€435.00
In stock
SKU
AC-AT1261a
Catalog Number: AC-AT1261a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB
Request Information AC-AT1261a">Request Information
Background:
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
Other Names:
BAG family molecular chaperone regulator 2, BAG-2, Bcl-2-associated athanogene 2, BAG2
Antigen Type:
Recombinant Protein
Gene Name: BAG2
Gene ID: 9532
NCBI Accession: NP_004273.1
Primary Accession: O95816
Other Accession: NM_004282
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
Other Names:
BAG family molecular chaperone regulator 2, BAG-2, Bcl-2-associated athanogene 2, BAG2
Antigen Type:
Recombinant Protein
Gene Name: BAG2
Gene ID: 9532
NCBI Accession: NP_004273.1
Primary Accession: O95816
Other Accession: NM_004282
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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