BAIAP2 polyclonal (C-term), anti-human, mouse

Background:
BAIAP2, a target of p53, has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This interaction at the cytoplasmic membrane is crucial to the function of this protein, which may be involved in neuronal growth-cone guidance. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis.

Other Names:
Brain-specific angiogenesis inhibitor 1-associated protein 2, BAI-associated protein 2, BAI1-associated protein 2, Protein BAP2, Fas ligand-associated factor 3, FLAF3, Insulin receptor substrate p53/p58, IRS-58, IRSp53/58, Insulin receptor substrate protein of 53 kDa, IRSp53, Insulin receptor substrate p53, BAIAP2

Target/Specificity:
This BAIAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 492-518 amino acids from the C-terminal region of human BAIAP2.

Antigen Region:
492-518

Antigen Type: Synthetic Peptide
Primary Accession: Q9UQB8-5
NCBI Accession: NP_001138360.1;NP_006331.1;NP_059344.1;NP_059345.1
Other Accession: NP_006331
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.