BAK1 polyclonal, anti-human

Background:
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

Synonyms: BAK, CDN1, BCL2L7, BAK-LIKE

Cellular Location: Cytoplasm

Immunogen:
Recombinant protein of human BAK1

Gene Symbol: BAK1

Gene ID: 578

Swiss prot: Q16611

Calculated MW: 23kDa

Recommended dilution:
WB 1:2000-5000, IHC 1:25-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.