BAK1 Polyclonal Antibody

Background:
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

Research Area: Cancer, Cell Biology

Synonyms:
Apoptosis regulator BAK, BAK, BAK like, Bak NT, BAK, Bak1, Bcl 2 homologous antagonist/killer, Bcl 2 like 7 protein, Bcl-2 homologous antagonist/killer, Bcl-2-like protein 7, BCL2 antagonist/killer 1, Bcl2 like 7 Protein, Bcl2-L-7, BCL2L7, CDN1, Cell death inhibitor 1, MGC117255, MGC3887, NBak, Pro apoptotic protein BAK

Immunogen: Recombinant protein of human BAK1

Swissprot: Q16611
Gene Accession: BC004431

Calculated MW: 23 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: WB 1:1000-1:5000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-1035/sc-832/sc-7873