BAK1 Polyclonal Antibody

Background:
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

Research Area: Cancer, Cell Biology

Synonyms:
BAK1, BAK, BAK-LIKE, BCL2L7

Immunogen: A synthetic peptide of human BAK1 (NP_001179.1).

Swissprot: Q16611
Gene ID: 578

Calculated MW: 16 kDa/23 kDa
Observed MW: 26 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.