BAK1 Polyclonal Antibody

Background:
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

Research Area: Cancer, Cell Biology

Synonyms:
Apoptosis regulator BAK, BAK, BAK like, Bak NT, BAK, Bak1, Bcl 2 homologous antagonist/killer, Bcl 2 like 7 protein, Bcl-2 homologous antagonist/killer, Bcl-2-like protein 7, BCL2 antagonist/killer 1, Bcl2 like 7 Protein, Bcl2-L-7, BCL2L7, CDN1, Cell death inhibitor 1, MGC117255, MGC3887, NBak, Pro apoptotic protein BAK

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse BAK

Swissprot: Q16611,O08734

Calculated MW: 25 kDa
Observed MW: 25 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Concentration: 3.1 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.