BANF1 antibody (clone M2), anti-human, mouse, rat
€435.00
In stock
SKU
AC-AT1267a
Catalog Number: AC-AT1267a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IF, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IF, E
Request Information AC-AT1267a">Request Information
Background:
The protein encoded by this gene was first identified by its ability to protect retroviruses from intramolecular integration and therefore promote intermolecular integration into the host cell genome. The protein forms a homodimer which localizes to both the nucleus and cytoplasm and is specifically associated with chromosomes during mitosis. This protein binds to double stranded DNA in a non-specific manner and also binds to LEM-domain containing proteins of the nuclear envelope. This protein is thought to facilitate nuclear reassembly by binding with both DNA and inner nuclear membrane proteins and thereby recruit chromatin to the nuclear periphery. Alternative splicing results in multiple transcript variants encoding the same protein.
Other Names:
Barrier-to-autointegration factor, Breakpoint cluster region protein 1, Barrier-to-autointegration factor, N-terminally processed, BANF1, BAF, BCRG1
Antigen Type:
Recombinant Protein
Gene Name: BANF1 {ECO:0000303|PubMed:21549337, ECO:0000312|HGNC:HGNC:17397}
Gene ID: 8815
NCBI Accession: NP_001137457.1;NP_003851.1
Primary Accession: O75531
Other Accession: BC005942
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene was first identified by its ability to protect retroviruses from intramolecular integration and therefore promote intermolecular integration into the host cell genome. The protein forms a homodimer which localizes to both the nucleus and cytoplasm and is specifically associated with chromosomes during mitosis. This protein binds to double stranded DNA in a non-specific manner and also binds to LEM-domain containing proteins of the nuclear envelope. This protein is thought to facilitate nuclear reassembly by binding with both DNA and inner nuclear membrane proteins and thereby recruit chromatin to the nuclear periphery. Alternative splicing results in multiple transcript variants encoding the same protein.
Other Names:
Barrier-to-autointegration factor, Breakpoint cluster region protein 1, Barrier-to-autointegration factor, N-terminally processed, BANF1, BAF, BCRG1
Antigen Type:
Recombinant Protein
Gene Name: BANF1 {ECO:0000303|PubMed:21549337, ECO:0000312|HGNC:HGNC:17397}
Gene ID: 8815
NCBI Accession: NP_001137457.1;NP_003851.1
Primary Accession: O75531
Other Accession: BC005942
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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