BANF1 polyclonal, anti-human, mouse, rat

Background:
Barrier-to-autointegration factor (BAF) binds non-specifically to double stranded DNA, possibly to play a role in tissue- or cell type-specific gene expression by interacting with different homeodomain transcription factors. BAF compresses chromatin structure and interacts with the LEM domain of nuclear proteins to play a crucial role in membrane recruitment and chromatin decondensation during nuclear assembly. Additionally, retroviruses like HIV-1 incorporate BAF from host cells into preintegration complexes (PICs) to prevent autointegration of retroviral DNA and thereby promote integration of retroviral DNA into the host chromosome.

Alternative Name:
BANF1, BAF, BCRG1, BAF, BAF, BANF 1, BANF1, Barrier to autointegration factor 1, Barrier to autointegration factor, Barrier-to-autointegration factor, BCRG 1, BCRG1, BCRP 1, BCRP1, Breakpoint cluster region protein 1, D14S1460, MGC111161, NGPS,

Application Dilution:
WB:1:500
ICC:1:50-1:100
IHC:1:50-1:200
FC:1:50-1:100

Specificity: BANF1 polyclonal antibody detects endogenous levels of BANF1 protein.

Immunogen:
Full length recombinant protein of human BANF1.

MW: 10 kDa

Swiss-Prot: O75531(Human) O54962(Mouse) Q9R1T1(Rat)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.