BAP1 Polyclonal Antibody
€0.00
In stock
SKU
ELK-ES10425
Catalog Number: ELK-ES10425
Reactivity: Human, Mouse, Rat
Applications: WB, ELISA
Information
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Questions? Contact us!
Reactivity: Human, Mouse, Rat
Applications: WB, ELISA
Information
Request Manual ELK-
Questions? Contact us!
Background:
BRCA1 associated protein 1(BAP1) Homo sapiens This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma. [provided by RefSeq, May 2013],
Immunogen: Synthesized peptide derived from human protein . at AA range: 150-230
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 80
GeneID: BAP1 KIAA0272 hucep-6
Storage: -20°C/1 year
NOTE: For Research Use Only
BRCA1 associated protein 1(BAP1) Homo sapiens This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma. [provided by RefSeq, May 2013],
Immunogen: Synthesized peptide derived from human protein . at AA range: 150-230
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 80
GeneID: BAP1 KIAA0272 hucep-6
Storage: -20°C/1 year
NOTE: For Research Use Only
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